Glikobiologija i esencijalni ugljikohidrati

undergraduate thesis

• Title (english): Glicobiology and essential carbohydrates
• Author: Iva Guberović
• Mentor: Domagoj Đikić (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; Zagreb
• Defense date and country: 2011-09-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

U ovom radu napravljen je presjek kroz polje glikobiologije da bi se prikazalo čime se ta znanost konkretno bavi. Donedavno se ugljikohidrate smatralo gotovo isključivo molekulama koje služe kao izvor energije, no zahvaljujući glikobiologiji, danas je poznato da se ti nutrijenti koriste, među ostalim, za sintezu glikokonjugata te ujedno sudjeluju u određivanju svojstava tih molekula. Ugljikohidrati u sklopu glikokonjugata imaju brojne funkcije vitalne za organizam kao što je imunološki odgovor, sprječavanje rasta i metastaziranja tumora, sudjelovanje u mijelinizaciji živaca i prenošenju živčanih signala, kao receptori za brojne tvari koje se proizvode u organizmu, ali i one koje se unose iz okoliša, za mikroorganizme i dr. Da bi se omogućilo izvršavanje svih tih funkcija glikokonjugata i šećera, zaslužni su lektini – proteini koji vežu ugljikohidrate te na taj način omogućuju izvršavanje njihovih funkcija. U radu su, također, ukratko opisani i glavni monosaharidi koji sudjeluju u izgradnji glikokonjugata te njihova uloga u sklopu glikokonjugata.

Abstract (english)

The purpose of the thesis was to make an overview of the field of glycobiology in order to explain the importance of this science. Until recently, carbohydrates were thought to be molecules whose sole function is to provide energy to the organism, but the field of glycobiology revealed that these nutrients are used for synthesis of glycoconjugates, and that they also determine properties of these compounds. Carbohydrates have numerous vital functions as part of glycoconjugates such as: taking part in immune response, preventing tumor growth and metastasis, inducing nerve myelination and conducting nerve signals, they act as receptors for molecules and compounds produced by the body or the ones that are coming from the environment, including microorganisms etc. Performance of glycoconjugates and sugars is enabled by lectins – proteins that bind carbohydrates and that take part in the functioning of these molecules. The thesis show which are the main monosaccharides comprised in the glycoconjugates and shortly explains their role.

• Keywords: glikobiologija; ugljikohidrati; glikokonjugati; lektini
• Keywords (english): Glycobiology; carbohydrates; glycoconjugates; lectins
• Language: croatian
• URN:NBN: urn:nbn:hr:159:921878
• Study programme: Title: Nutrition; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-05-19 12:16:48