Antimikrobno djelovanje novosintetiziranih analoga kumarina i dehidrooctene kiseline

master's thesis

• Title (english): Antimicrobial effect of newly synthesized analogues of coumarin and dehydroacetic acid
• Author: Lejla Šećerkadić
• Mentor: Senadin Duraković (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Biochemical Engineering); (Laboratory for General Microbiology and Food Microbiology); Zagreb
• Defense date and country: 2009-12-18, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Food Technology

Abstract

Dehidrooctena kiselina (DHA) se ubraja među djelotvorne kemijske agense s antimikrobnim svojstvima. Nakon brojnih istraživanja smatralo se da je zbog niske toksičnosti za organizme sisavaca i zbog efikasnosti u zaštiti mikrobne kontaminacije moguća njezina široka upotreba. Dehidrooctena kiselina prihvaćena je kao konzervans i aditiv u prehrambenim proizvodima. Koristi se u organskim sintezama, a uz to ima široku primjenu u poljoprivredi kao pesticid i učinkoviti fungicid. Kumarini su vrlo važna grupa organskih spojeva koji se prirodno pojavljuju u mnogim vrstama, osobito trava. Koriste se u sintezi lijekova budući da su prekursori mnogih antikoagulanata. Derivati kumarina obično se pojavljuju kao sekundarni metaboliti u mnogih biljaka, no njihova funkcija još nije dovoljno razjašnjena. Biološkim pokusima odavno je utvrđeno da kumarin ima toksička, kancerogena i mutagena svojstva.

Abstract (english)

Dehydroacetic acid (DHA) belongs to effective chemical agents with antimicrobial properties. After much research, it was believed that DHA can be widely used due to its low toxicity for mammal organisms and due to efficient protection from microbial contamination. DHA is accepted as a preservative and an additive in food products. It is used in organic syntheses, and it is also widely used in agriculture as a pesticide and an efficient fungicide. Coumarins are a very important group of organic compounds which occur naturally in many species, particularly in plants. They are used in the synthesis of drugs, since they are precursors of many anticoagulants. Coumarine derivatives usually occur as secondary metabolites in many plants, but their function still hasn’t been sufficiently clarified. Biological tests have long ago shown that coumarin has toxic, carcinogenic, and mutagenic properties.

• Keywords: bakterije; dehidrooctena kiselina; kvasci; kumarin; plijesni
• Keywords (english): bacterias; coumarin; dehydroacetic acid; moulds; yeasts
• Language: croatian
• URN:NBN: urn:nbn:hr:159:763758
• Study programme: Title: Food Technology; specializations in: Food Engineering; Course: Food Engineering; Study programme type: university; Study level: graduate; Academic / professional title: diplomirani inženjer prehrambene tehnologije; smjer prehrambeno inženjerstvo (diplomirani inženjer prehrambene tehnologije; smjer prehrambeno inženjerstvo)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-09-01 10:01:38