Određivanje sadržaja amoksicilina u veterinarsko-medicinskim pripravcima HPLC metodom

master's thesis

• Title (english): HPLC determination of amoxicillin assay in veterinary-medicinal preparations
• Author: Sandra Miler
• Mentor: Jasna Vorkapić-Furač (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Biochemical Engineering); Zagreb
• Defense date and country: 2008-07-11, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

Tekućinskom kromatografijom visoke djelotvornosti (HPLC) validirana je analitička metoda za određivanje sadržaja amoksicilina u veterinarsko medicinskim pripravcima. Određeni su parametri selektivnosti, linearnosti i ponovljivosti. Rezultati su pokazali da metoda zadovoljava sve postavljene kriterije i smatra se prikladnom za predviđenu buduću uporabu. Kako bi povećali sigurnost mjernog rezultata izračunata je mjerna nesigurnost metode. Kao izvori mjerne nesigurnosti prepoznati su standard, priprema uzorka, baždarni pravac i ponovljivost.

Abstract (english)

HPLC analytical method for assay determination of amoxicillin in veterinary-medicinal preparations was validated. Analitycal method characteristics such as specifity, linearity and precision were determined. The method complies with all requirementes and can be considered valid for future usage. In order to decide whether a result indicates compliance or non-compliance with a specification the measurement uncertainty associated with the result were taken into account. The uncertainty of the result arise from many possible sources like standard solution preparation, sampling, calibration and precision.

• Keywords: amoksicilin; HPLC; mjerna nesigurnost; validacija
• Keywords (english): amoxicillin; HPLC; measurement uncertainty; validation
• Language: croatian
• URN:NBN: urn:nbn:hr:159:061919
• Study programme: Title: Biotechnology; specializations in: Biochemical Engineering; Course: Biochemical Engineering; Study programme type: university; Study level: graduate; Academic / professional title: diplomirani inženjer biotehnologije; smjer biokemijsko inženjerstvo (diplomirani inženjer biotehnologije; smjer biokemijsko inženjerstvo)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-09-01 12:25:37