Razvoj i validacija automatizirane analitičke metode za određivanje ujednačenosti jedinične doze u Cilazil tabletama

master's thesis

• Title (english): Development and validation of automated HPLC analytical method for assay determination of uniformity of dosage units in Cilazil tablets
• Author: Ana Kordić
• Mentor: Jasna Vorkapić-Furač (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Biochemical Engineering); (Laboratory for Cell Technology, Application and Biotransformations); Zagreb
• Defense date and country: 2006-05-09, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

Tekućinskom kromatografijom visoke djelotvornosti (HPLC) validirana je automatizirana analitička metoda za određivanje ujednačenosti jedinične doze u Cilazil tabletama. Određeni su parametri selektivnosti, linearnosti, točnosti, stabilnosti otopina i robustnosti te su određeni kriteriji prikladnosti kromatografskog sustava i radno područje metode. Metoda zadovoljava sve postavljene kriterije i smatra se prikladnom za predviđenu namjenu.

Abstract (english)

Automated analytical method for assay determination of uniformity of dosage units in Cilazil tablets was validated by HPLC. Analytical method characteristics such as specifity, linearity, accuracy, stability of solution and robustness, as well as system suitability testing and range of method were determined by HPLC. The method complies with all requirements and can be considered valid for intended purpose.

• Keywords: Cilazil; HPLC; validacija metode
• Keywords (english): Cilazil; HPLC; validation method
• Language: croatian
• URN:NBN: urn:nbn:hr:159:524976
• Study programme: Title: Biotechnology; specializations in: Biochemical Engineering; Course: Biochemical Engineering; Study programme type: university; Study level: graduate; Academic / professional title: diplomirani inženjer biotehnologije; smjer biokemijsko inženjerstvo (diplomirani inženjer biotehnologije; smjer biokemijsko inženjerstvo)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-09-08 11:54:17