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undergraduate thesis
Priprava ferocenskog muropeptida
2019. urn:nbn:hr:159:420125
Martinić-Cezar, Tea
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Chemistry and Biochemistry
Laboratory for Organic Chemistry

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Martinić Cezar, T. (2019). Priprava ferocenskog muropeptida (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:420125

Martinić Cezar, Tea. "Priprava ferocenskog muropeptida." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2019. https://urn.nsk.hr/urn:nbn:hr:159:420125

Martinić Cezar, Tea. "Priprava ferocenskog muropeptida." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2019. https://urn.nsk.hr/urn:nbn:hr:159:420125

Martinić Cezar, T. (2019). 'Priprava ferocenskog muropeptida', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 10 July 2024, https://urn.nsk.hr/urn:nbn:hr:159:420125

Martinić Cezar T. Priprava ferocenskog muropeptida [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2019 [cited 2024 July 10] Available at: https://urn.nsk.hr/urn:nbn:hr:159:420125

T. Martinić Cezar, "Priprava ferocenskog muropeptida", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:159:420125

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Metadata
TitlePriprava ferocenskog muropeptida
Title (english)Synthesis of ferrocene muropeptide
AuthorTea Martinić-Cezar
MentorMonika Kovačević (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Chemistry and Biochemistry)
(Laboratory for Organic Chemistry)
Zagreb
Defense date and country2019-07-09, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Muramildipeptid je produkt koji nastaje enzimskom razgradnjom peptidoglikana, sastavnog dijela stanične stijenke Gram-pozitivnih i Gram-negativnih bakterija. Kemijski gledano, oni su konjugati muraminske i prirodnih aminokiselina, koji imaju ulogu imunoadjuvanata. Posjeduju veliki potencijal te se koriste u terapeutske svrhe kao imunostimulatorni spojevi. U ovom radu opisani su sinteza i konformacijska svojstva ferocenskog muropeptida 5 koji nastaje kopulacijom C- terminusa muraminske kiseline 4 i N- terminusa ferocenske aminokiseline 3. Na temelju rezultata NMR- i IR-spektroskopije predloženi su najstabilniji konformeri.
Abstract (english)
Muropeptides are degradation fragments of Gram(+) and Gram(-) peptidoglycan (PGN), produced by enzymatic degradation of bacterial cell wall. From chemical point of view, muropeptides are conjugates of muramic and natural amino acids with adjuvant properties. They have great potential acting as therapeutic agents with immunostimulating activity. This study has explored the synthesis and structural characteristics of ferrocene muropeptide 5 derived by coupling of C- terminus of muramic acid 4 and N- terminus of ferrocene amino acid 3. Based on NMR- and IR-spectroscopy the preferable conformations were proposed.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:420125
Study programmeTitle: Food Technology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2019-07-16 10:28:35