Molekularno-biološki faktori razvoja tumora zametnih stanica testisa

undergraduate thesis

• Title (english): Molecular-biological factors in development of testicular germ cells tumors
• Author: Sunčana Orešić
• Mentor: Tomislav Vladušić (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Biochemical Engineering); (Laboratory for Biology and Microbial Genetics); Zagreb
• Defense date and country: 2019-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

Tumori su i dan danas jedan od većih misterija medicine, posebice faktori i mehanizmi njihovog nastajanja i razvoja. Tumori testisa, specijalno zametnih stanica testisa, još uvijek su podosta nepoznat teritorij, unatoč visokoj razini proučenosti. Jedan su od vodećih uzroka smrtnosti muškaraca, a postaju i sve češći u populaciji. U radu ću se osvrnuti na dosad poznate molekularno-biološke faktore nastanka i razvoja tumora zametnih stanica testisa (genske promjene, epigenske promjene, nasljednost i utjecaj vanjskih faktora) te na njihov značaj za sadašnjost i budućnost poznavanja, dijagnosticiranja i liječenja tumora.

Abstract (english)

Up to this day, tumours remain one of the greatest medical mysteries, especially their development factors and mechanisms. Testicular tumours, especially testicular germ cells tumours, are still quite an unknown territory, despite being highly studied. They are one of the leading causes of death amogst men, and their number is increasing. In this thesis, I will write about known molecular-biological factors of testicular germ cells tumor development (genetic alterations, epigenetic alterations, inheritance and environmental factors) and their importance in the present and the future of knowing, diagnosing and treating tumours.

• Keywords: ekspresija gena; epigenetika; neseminom; seminom; terapija; tumor zametnih stanica testisa
• Keywords (english): epigenetics; gene expression; non-seminoma; seminoma; testicular germ cells tumor; therapy
• Language: croatian
• URN:NBN: urn:nbn:hr:159:181410
• Study programme: Title: Biotechnology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2019-07-26 07:54:21