Analiza efektivne difuzivnosti galne kiseline kao modelnog supstrata za analizu vodenih ekstrakcija u mikroreaktorima

undergraduate thesis

• Title (english): Analysis of effective diffusivity of gallic acid as a model substrate for analysis of aqueous extractions in microreactors
• Author: Paula Inkret
• Mentor: Davor Valinger (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Process Engineering); (Laboratory for Measurement, Regulation and Automatisation); Zagreb
• Defense date and country: 2019-09-18, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

Iako se još uvijek većina kemijskih i biokemijskih reakcija u laboratorijima odvija u reaktorima velikih volumena, mikroreaktori su posljednjih 20 godina postali vrlo zanimljivi zbog niskih operacijskih troškova, većih efikasnosti procesa i prinosa te mogućnosti provođenja reakcija s vrlo nestabilnim i brzo razgradivim intermedijerima. U sklopu razvoja novog mikroreaktorskog sustava u ovom radu korištena je galna kiselina kao modelni supstrat u mikroreaktoru glatkih stijenki s Y-ulazom i Y-izlazom aktivnog volumena 4 μL. Cilj ovoga rada bio je na temelju eksperimentalnih podataka razviti model efektivne difuzivnosti galne kiseline kao modelnog supstrata za razne mikroreaktorske analize vodenih ekstrakata. Rezultat simulacije matematičkog modela procesa difuzije riješenog aproksimativnom metodom (mikroreaktor je opisan s dva idealna cijevna reaktora) dao je vrlo dobra slaganja s eksperimentalnim podacima. Pomoću razvijenog modela, predviđene su i efektivne difuzivnosti galne kiseline za koncentracije koje nisu mjerene te je prikazano kako širina kanala mikroreaktora utječe na brzinu efektivne difuzivnosti.

Abstract (english)

Although most of the chemical and biochemical reactions in laboratories still take place in large volume reactors, microreactors have become very popular over the last 20 years due to low operating costs, higher process and yield efficiency and the ability to carry out reactions with highly unstable and rapidly degradable intermediates. As part of the development of a new microreactor system, in this work, gallic acid was used as a model substrate in a smooth surface micro-channel walls microreactor equipped with Y-shape inlet and Y-shape outlet with active volume of V = 4 μL. The aim of this work was to develop a model of gallic acid effective diffusivity (used as substrate model for microreactor analysis of aqueous extracts) based on experimental data. The result of the mathematical model simulation for the diffusion process which was solved by an approximate method (a microreactor was described by two ideal tube reactors) gave very good agreement with the experimental data. The developed model also gave very good predictions of effective diffusivity for the concentrations of gallic acid that were not measured and showed how the width of the microreactor channel influences the speed of effective diffusivity.

• Keywords: efektivna difuzivnost; galna kiselina; mikroreaktor; modeliranje mikroreaktorskih sustava
• Keywords (english): effective diffusivity; gallic acid; microreactor; modeling of microreactors
• Language: croatian
• URN:NBN: urn:nbn:hr:159:275940
• Study programme: Title: Biotechnology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2019-09-23 09:40:25