Utjecaj prehrane, stupnja uhranjenosi i životnih navika na disbiozu crijevne mikrobiote

master's thesis

• Title (english): The effect of diet, body mass index and lifestyle on intestinal microbiota dysbiosis
• Author: Ivona Grilec
• Mentor: Ivana Rumora Samarin (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Food Chemistry and Biochemistry); Zagreb
• Defense date and country: 2019-03-26, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Crijevna mikrobiota je kompleksna zajednica mikroorganizama čiji je sastav u pojedinca promijenjiv tijekom vremena, ali zadržava zajedničke karakteristike. Pod utjecajem određenih čimbenika, od kojih se u posljednje vrijeme ističe prehrana, može doći do narušene ravnoteže u sastavu crijevne mikrobiote odnosno disbioze. Disbioza crijevne mikrobiote povezuje se s različitim bolestima poput pretilosti, upalnih bolesti crijeva, sindroma iritabilnog crijeva, karcinoma debelog crijeva, kardiovaskularnih bolesti, metaboličkog sindroma, anoreksije, alergije i astme. Cilj ovog istraživanja bio je utvrditi postoji li zajednička poveznica između prehrane, antropometrijskih i biokemijskih parametara te životnih navika i disbioze crijevne mikrobiote, odnosno povećane zastupljenosti reda Enterobacteriales koja je utvrđena kod ispitanika (n=3) prilikom istraživanja utjecaja stupnja uhranjenosti sa sastavom crijevne mikrobiote mlađe populacije. S obzirom na nekonzistentnost dobivenih rezultata, nije pronađena zajednička poveznica u unosu makronutrijenata i prehrambenih vlakana, antropometrijskim i biokemijskim parametrima te životnim navikama koja bi mogla dovesti do očitovane disbioze crijevne mikrobiote.

Abstract (english)

Intestinal microbiota is a complex microbial community whose composition in the individual can be changed over time, but retains common characteristics. The composition of intestinal microbiota can be disrupted under the influence of certain factors, of which diet is hypothesized as a major factor. Intestinal microbiota dysbiosis is associated with various diseases such as obesity, inflammatory bowel disease, irritable bowel syndrome, colon cancer, cardiovascular diseases, metabolic syndrome, anorexia, allergies and asthma. The aim of this study was to determine whether there is a common link between diet, anthropometric parameters, biochemical parameters, life habits and dysbiosis, respectively increased representation of Enterobacteriales order found in subjects (n=3) during studying the influence of body mass index on the intestinal microbiota composition in the younger population. Considering the inconsistency of the obtained results no common link was found in the macronutrient and dietary fiber intake, anthropometric and biochemical parameters and life habits that could lead to manifested intestinal microbiota dysbiosis.

• Keywords: crijevna mikrobiota; disbioza; prehrana; indeks tjelesne mase
• Keywords (english): intestinal microbiota; dysbiosis; diet; body mass index
• Language: croatian
• URN:NBN: urn:nbn:hr:159:247451
• Study programme: Title: Nutrition; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2019-12-10 07:37:30