Posljedice nedostatka vitamina D i toksikološki aspekti prekomjernog unosa

undergraduate thesis

• Title (english): Vitamin D deficiency and toxicological aspects of overdose
• Author: Dora Bobovčan
• Mentor: Ivana Kmetič (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Chemistry and Biochemistry); (Laboratory for Toxicology); Zagreb
• Defense date and country: 2021-09-16, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Deficit vitamina D dovodi do mnogobrojnih zdravstvenih problema, od kojih su najbitniji javnozdravstveni problemi povezani s koštanim sustavom, pogotovo u osoba starije životne dobi, djece i adolescenata. U posljednje vrijeme svjedoci smo povećane marketinške kampanje, kao i smjernica javnozdravstvenih tijela za suzbijanje prevencije deficita, koji su doveli do velikog porasta potrošnje dodataka prehrani vitamina D u raznim oblicima. No, većina konzumenata uzima dodatke i samopropisuje doze, bez liječničkog nadzora i edukacije o potencijalnoj štetnosti dodataka vitamina D. Stoga, sve je veća pojavnost slučajeva intoksikacije vitaminom D, pogotovo u djece, gdje roditelji daju djeci velike doze u tekućem obliku. Osim nepravilnog doziranja koje je opasno, dodaci prehrani mogu biti često kontaminirani teškim metalima, koji predstavljaju opasnost za zdravlje, pogotovo uz kronični unos. Stoga, suplementacija vitaminom D treba biti pod nadzorom stručne osobe i kod zdravih osoba treba započeti suplementaciju tek kada je ustanovljen deficit.

Abstract (english)

Vitamin D deficiency can lead to an onset of health problems, including a major public health problems with skeletal system, especially for the groups considered in risk of deficit- elderly, children and adolescents. Through marketing and public raising awareness for deficiency prevention, vitamin D supplements have become very popular. The problem with increased supplementation is that consumers take self-prescribed doses, without medical supervision and education on potential harm of vitamin D supplements. Therefore, there is an increasing incidence of cases of vitamin D intoxication, especially in children, where parents give children overdoses in liquid form. Apart from megadoses, dietary supplements are also very likely to be contaminated with heavy metals, which are a health hazard when being ingested during a long period of time. Therefore, vitamin D supplementation should only be prescribed for clinically confirmed deficiency or under supervision of a professional.

• Keywords: doza; intoksikacija; kontaminacija; toksičnost; vitamin D
• Keywords (english): contamination; dose; intoxication; toxicity; vitamin D
• Language: croatian
• URN:NBN: urn:nbn:hr:159:180728
• Study programme: Title: Nutrition; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-09-28 09:18:03