Utjecaj kurkumina na zdravlje

undergraduate thesis

• Title (english): Curcumin effects on health
• Author: Marin Maglica
• Mentor: Irena Landeka Jurčević (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Food Chemistry and Biochemistry); Zagreb
• Defense date and country: 2023-09-14, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Biljka kurkuma (Curcuma longa L.) je stoljećima korištena u tradicionalnoj medicini zbog svojih pozitivnih učinaka na ljudsko zdravlje, a u kulinarstvu kao začin specifičnog okusa i boje koju daje jelima. U korijenu biljke su sadržani aktivni spojevi kurkuminoidi, polifenoli odgovorni za njena ljekovita svojstva. Većina pozitivnih učinaka na zdravlje pripisuje se antioksidativnom i protuupalnom djelovanju kurkumina. Može pomoći u poboljšanju kvalitete života i smanjenju progresije kod bolesti poput raka, dijabetesa, artritisa, neurodegenerativnih bolesti, metaboličkog sindroma, bolesti jetre i bubrega i dr., što ga čini popularim predmetom istraživanja u različitim područjima biomedicine. Najveći problem suplementacije kurkuminom jest loša bioraspoloživost zbog čega su patentirane i korištene formulacije i nanoformulacije kurkumina. One sadrže različite spojeve koji djeluju kao poboljšivači bioraspoloživosti, a najčešće korišten spoj u tu svrhu jest piperin. Kurkumin se smatra sigurnim, iako u prekomjernim dozama može izazvati blage gastrointestinalne smetnje i glavobolju.

Abstract (english)

For centuries, turmeric plant (Curcuma longa L.) is used in traditional medicine due to its positive effects on human health, in culinary arts as s spice which gives food specific flavor and colour. Turmeric root contains active ingredients called curcuminoids, polyphenols responsible for its medicinal properties. Most health benefits come from antioxidant and anti-inflammatory activity of curcumin. It can aid in improving life quality but also decrease progression in diseases such as cancer, diabetes, arthritis, neurodegenerative diseases, metabolic syndrome, liver and kidney diseases etc., which makes him popular subject of research in different areas of biomedicine. The biggest issue with curcumine supplementation is its poor bioavailabillity which is why formulations and bioformulations of curcumin are being patented and used. They contain added compounds which act as bioavailabillity enhancers, piperine is the most commonly used in that purpose. Curcumin is considered safe, although in large doses can cause minor gastrointestinal issues and headaches.

• Keywords: Kurkumin; Curcuma longa; zdravlje
• Keywords (english): Curcumin; Curcuma longa; health
• Language: croatian
• URN:NBN: urn:nbn:hr:159:044655
• Study programme: Title: Nutrition; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-04-18 09:14:31