Metabolička uloga kolagena i dodataka prehrani

undergraduate thesis

• Title (english): Role of collagen and food supplements in metabolism
• Author: Barbara Gabrić
• Mentor: Irena Landeka Jurčević (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Food Chemistry and Biochemistry); Zagreb
• Defense date and country: 2023-07-14, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Interdisciplinary Technical Sciences

Abstract

Kolagen je najzastupljeniji protein kod sisavaca, uglavnom prisutan u vezivnim tkivima. Karakterizira ga neobičan aminokiselinski sastav. Sadrži velike količine glicina i prolina, kao i dvije aminokiseline koje ne ubacuju izravno ribosomi, a to su hidroksiprolin i hidroksilizin. Starenjem udio kolagena u ljudskom organizmu smanjuje se linearno za 1% godišnje. Lako se može izolirati iz različitih životinjskih izvora, te integrirati u različite suplemente, kao što su razni oblici sirupa, kapsula, tableta, prahova. Hidrolizirani oblik kolagena dobro se apsorbira u krvotok, što mu omogućava sudjelovanje u obnavljanju kože, hrskavice, zglobova, kose, noktiju. Kao učinkovit dodatak prehrani pokazali su se i suplementi koji potiču sintezu kolagena. To su vitamin C, koji je neophodan kofaktor u sintezi kolagena, i kolinom stabilizirana ortosilicijeva kiselina, tj. ch-OSA, koja djelovanjem enzima aktivira biološke puteve za stvaranje kolagena.

Abstract (english)

Collagen is the most abundant protein in mammals, mostly found in connective tissues. It is characterized by an unusual amino acidic composition. It contains high amounts of glycine and proline, as well as two amino acids not inserted directly by ribosomes – hydroxyproline and hydroxylysine. With age, the amount of collagen in the human organism decreases in a linear manner by 1% annually. Collagen can be easily isolated from numerous animal sources, and integrated into diverse supplements, such as various forms of syrups, capsules, pills and powders. The hydrolyzed variety of collagen is easily absorbed into the bloodstream, which enables it to participate in regeneration of skin, cartilage, hair, joints and nails. Also, supplements that stimulate collagen synthesis have proven to be effective dietary supplements. These being vitamin C, which is a necessary cofactor in collagen synthesis, and cholinestabilized orthosilicic acid, i.e., ch-OSA, which activates biological ways of collagen formation through the action of enzymes.

• Keywords: kolagen; kolinom stabilizirana ortosilicijska kiselina (ch-OSA); hidrolizati kolagena
• Keywords (english): choline; choline-stabilized orthosilicic acid (ch-OSA); collagen hydrolysates
• Language: croatian
• URN:NBN: urn:nbn:hr:159:364319
• Study programme: Title: Food Technology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-05-06 11:26:16