Osobitosti nadomjesne primjene vitamina D u bolesnika s pretilošću

master's thesis

• Title (english): Characteristics of vitamin D replacement in patients with obesity
• Author: Klara Rađa
• Mentor: Darija Vranešić Bender (mentor)
• Mentor: Martina Matovinović Osvatić (komentor)
• Committee member: Ines Panjkota-Krbavčić (predsjednik povjerenstva)
• Committee member: Martina Matovinović Osvatić (član povjerenstva)
• Committee member: Jasenka Gajdoš Kljusurić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Nutrition Science); Zagreb
• Defense date and country: 2023-09-25, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Znanstvenici pokazuju povećani interes za istraživanje utjecaja suplementacije vitamina D na liječenje pretilosti i drugih bolesti povezanih s manjkom ovog vitamina. Cilj rada bio je utvrditi odgovor na nadomjesne primjene vitamina D u bolesnika s pretilošću s obzirom na primijenjene doze vitamina D, vrijednosti indeksa tjelesne mase (ITM) te metaboličkog panela biokemijskih parametara. Istraživanje je obuhvatilo 53 pacijenta, 42 žene i 11 muškaraca, dobi 22-72 godine. Utvrđena je slaba povezanost između ITM i vitamina D u krvi (p < 0,05) kod pacijenata koji su početno bili u prvom i drugom stupnju pretilosti, dok je izrazito jaka povezanost između ova dva parametra (p < 0,001) uočena kod pacijenata s početnim trećim stupnjem pretilosti. Nakon provedene suplementacije status vitamina D povećao se kod 56,6 % pacijenata. Nije utvrđena povezanost između ITM i nadomjesne terapije vitaminom D što pokazuje da suplementacija nema utjecaja na liječenje pretilosti.

Abstract (english)

Scientists have shown a growing interest in researching the impact of vitamin D supplementation on the treatment of obesity and other diseases associated with its deficiency. This work aimed to determine the response to replacement administration of vitamin D in patients with obesity concerning the applied doses of vitamin D, body mass index (BMI) values, and metabolic panel of biochemical parameters. The research included 53 patients, 42 women and 11 men, aged 22-72. A weak association between BMI and blood vitamin D (p < 0.05) was found in patients who were initially in the first and second degree of obesity. A very strong association between two parameters (p < 0.001) was observed in patients with initial third degree of obesity. After supplementation, vitamin D status increased in 56.6 % of patients. No association was found between BMI and vitamin D replacement therapy, indicating that supplementation does not affect obesity treatment.

• Keywords: pretilost; manjak vitamina D; suplementacija vitaminom D; nadomjesne doze vitamina D
• Keywords (english): obesity; vitamin D deficiency; vitamin D supplementation; replacement doses of vitamin D
• Language: croatian
• URN:NBN: urn:nbn:hr:159:790911
• Study programme: Title: Nutrition; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-06-06 13:40:11