Procjena nutritivnog i metabličkog statusa te pridržavanja mediteranskog obrasca prehrane kod osoba s dijagnozom predijabetesa ili dijabtetesa tipa 2

master's thesis

• Title (english): Assessment of nutritional and metabolic status and adherence to the Mediterranean diet in persons with prediabetes or type 2 diabetes diagnosis
• Author: Karmen Černak
• Mentor: Darija Vranešić Bender (mentor)
• Committee member: Martina Bituh (predsjednik povjerenstva)
• Committee member: Zvonimir Šatalić (član povjerenstva)
• Committee member: Jasenka Gajdoš Kljusurić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Nutrition Science); Zagreb
• Defense date and country: 2023-09-26, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Primarni cilj ovog rada je bio istražiti utjecaj mediteranske prehrane na razinu glukoze u krvi kod oboljelih od predijabetesa i dijabetesa tipa 2. Pridržavanje mediteranske prehrane procjenjivalo se na 303 pacijenta Kliničkog bolničkog centra Zagreb i Kliničke bolnice Sveti Duh uz pomoć MEDAS (engl. Mediterranean Diet Adherence Screener) upitnika prilagođenog hrvatskom jeziku. Pacijenti su imali manji omjer izgleda (OR = 0,40) za HbA1c (engl. glycated haemoglobin) ≥6 % ako su postigli veće vrijednosti na upitniku (4 – 6 od maksimalno 14) uz statističku značajnost p= 0,015. Rezultati su potvrdili pozitivan učinak mediteranske prehrane na regulaciju glukoze u krvnoj plazmi. Nije uočena statistički značajna povezanost mediteranske prehrane i lipidnog profila (ukupni kolesterol (p = 0,280), LDL (engl. low-density lipoprotein) (p = 0,446) i HDL (engl. high density lipoprotein) (p = 0,454)). Indeks tjelesne mase (ITM) je negativno povezan s ukupnim MEDAS score-om (OR = - 0,46, p = 0,015).

Abstract (english)

Primary goal of this work was to investigate influence of Mediterranean diet on blood glucose levels in patients with prediabetes and type 2 diabetes. Adherence to Mediterranean diet was assessed in 303 patients of Zagreb Clinical Hospital Center and Clinical Hospital Sveti Duh with the help of MEDAS (Mediterranean Diet Adherence Screener) questionnaire adapted to Croatian language. Patients had lower odds ratio (OR = 0,40) for HbA1c (glycated haemoglobin) ≥6 % if they achieved higher values on questionnaire (4 - 6 out of maximum 14) with statistical significance p = 0,015. Results confirmed positive effect of Mediterranean diet on regulation of glucose in blood plasma. No statistically significant association between Mediterranean diet and lipid profile was observed (total cholesterol (p = 0,280), LDL (low-density lipoprotein) (p = 0,446) and HDL (high-density lipoprotein) (p = 0,454)). Body mass indeks (BMI) was negatively associated with total MEDAS score (OR = - 0,46, p = 0,015).

• Keywords: predijabetes; dijabetes tip 2; mediteranska prehrana; MEDAS
• Keywords (english): prediabetes; diabetes type 2; Mediterranean diet; MEDAS
• Language: croatian
• URN:NBN: urn:nbn:hr:159:297615
• Study programme: Title: Nutrition; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-06-10 09:29:39