Prehrambeni čimbenici i status vitamina D u djece s atopijskim dermatitisom

master's thesis

• Title (english): Nutrition and vitamin D status in children with atopic dermatitis
• Author: Petra Pejnović
• Mentor: Darija Vranešić Bender (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Nutrition Science); Zagreb
• Defense date and country: 2017-09-26, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Atopijski dermatitis (AD) kronična je alergijska bolest s prevalencijom 15-30% kod djece. Cilj ovog ispitivanja je utvrđivanje povezanosti vitamina D i pojave atopijskog dermatitisa kod djece starosti do 10 godina. Brojne randomizirane kliničke studije pokazale su da vitamin D može ublažiti simptome atopijskog dermatitisa. U istraživanju je sudjelovalo 18 pacijenata oboljelih od atopijskog dermatitisa. Roditelji ispitanika ispunili su Upitnik o općim podacima te prehrambenim navikama djeteta, te su vodili 3-dnevni dnevnik prehrane. Svim ispitanicima izračunata je EASI (Eczema Area and Severity Index) vrijednost, te je izmjerena razina 25(OH)D u krvi. Rezultati su pokazali kako je unos vitamina D putem hrane kod svih ispitanika izuzetno nizak (3,28±2,08 μg/dan), a kada se unosu putem hrane doda količina vitamina D iz dodataka prehrani, vrijednosti se značajno povećavaju samo u najmlađoj skupini. Također, nije pronađena statistički značajna povezanost statusa vitamina D u krvi ispitanika i EASI vrijednosti, što ukazuje na činjenicu da su potrebna daljnja istraživanja.

Abstract (english)

Atopic dermatitis (AD) is chronic allergic disease with prevalence 15-30% in children. This study aimed to investigate correlation between vitamin D status and atopic dermatitis in children aged 0-10 years old. Numerous clinical studies showed that vitamin D can moderate simptoms of AD. Parents filled out the Questionnaire with general data and patients nutritional habits and 3-day Food record. Also, EASI score was calculated and circulating 25(OH)D was measured to all 18 participants. Results revealed that the food intake of vitamin D was very low in all participants (3,28±2,08 μg/day), and combined with use of supplements, total intake only rised in the youngest age group. Also, statistical correlation was not found between vitamin D status and EASI score, what prove that further research is necessary.

• Keywords: atopijski dermatitis; vitamin D; alergija na hranu; EASI; djeca do 10 godina
• Keywords (english): atopic dermatitis; vitamin D; food allergy; EASI score; children
• Language: croatian
• URN:NBN: urn:nbn:hr:159:262388
• Study programme: Title: Nutrition; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2017-11-13 13:53:46