Vegetarijanska prehrana, nutritivni status vitamina B skupine i razina homocisteina kao čimbenici rizika za pojavu osteoporoze

doctoral thesis

• Title (english): Vegetarian diet, B vitamins nutritional status and homocysteine as risk factors for osteoporosis
• Author: Zvonimir Šatalić; MBZ: 249962
• Mentor: Irena Colić Barić (mentor); MBZ: 120646
• Committee member: Vladimir Mrša (predsjednik povjerenstva); MBZ: 39525
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; Zagreb
• Defense date and country: 2009-07-13, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Food Technology
• Universal decimal classification (UDC): 616 - Pathology. Clinical medicine

Abstract

Povišena razina homocisteina se smatra novim čimbenikom rizika za pojavu osteoporoze. Cilj ovog istraživanja bio je utvrditi trenutno nepoznat utjecaj često povišene razine homocisteina među vegetarijancima na mineralnu gustoću kosti (BMD). U istraživanju je sudjelovalo 102 vegetarijanca dobi 21-55 godina. Utvrđene su negativne korelacije razine homocisteina i BMD te pozitivne korelacije vitamina B12 i folata u eritrocitima s BMD (p<0,05) među muškarcima, ali ne i među ženama. Utvrđene su pozitivne korelacije (p<0,05) unosa folata hranom i dodacima prehrani s BMD među muškarcima, ali ne i među ženama. Povišena razina homocisteina među vegetarijancima ima negativan utjecaj na BMD.

Abstract (english)

Elevated homocysteine is newly recognized risk factor for osteoporosis. The aim of this study was to determine currently unknown relationship of often elevated homocysteine in vegetarians and bone mineral density (BMD). Subjects were 102 vegetarians 21-55 years old. Negative correlation was observed for homocysteine and BMD, and positive for vitamin B12 and red blood cell folate with BMD (p<0,05), but in men only. Positive correlation (p<0,05) for dietary folate intake including supplemental folic acid and BMD was observed in men, but not in women. Elevated homocysteine has an adverse effect on BMD in vegetarians.

• Keywords: BMD; folat; homocistein; prehrana; vegani; vegetarijanci; vitamin B12; vitamin D
• Keywords (english): BMD; folate; homocysteine; nutrition; vegans; vegetarians; vitamin B12; vitamin D
• Language: croatian
• URN:NBN: urn:nbn:hr:159:147761
• Promotion: 2010-07-04
• Study programme: Title: Postgraduate PhD Study in Nutrition; Study programme type: university; Study level: postgraduate; Academic / professional title: doktor/doktorica znanosti, područje biotehničkih znanosti, polje nutricionizam (doktor/doktorica znanosti, područje biotehničkih znanosti, polje nutricionizam)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2018-05-15 11:22:23