Biološka detoksifikacija i mehanizmi uklanjanja okratoksina A

undergraduate thesis

• Title (english): Biological detoxification and removal mechanisms of ochratoxin A
• Author: Lucija Vukšić
• Mentor: Ksenija Markov (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Biochemical Engineering); (Laboratory for General Microbiology and Food Microbiology); Zagreb
• Defense date and country: 2020-07-10, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

Okratoksin A (OTA) se smatra jednim od najopasnijih mikotoksina koji se nalaze u prehrambenim proizvodima, a kao glavni izvori OTA u ljudskoj prehrani navode se žitarice i vino. Istraživanja su pokazala da ima nefrotoksično, karcinogeno, imunotoksično, mutageno i neurotoksično djelovanje te je klasificiran kao mogući ljudski karcinogen. Osim preventivnih postupaka koji se primjenjuju kako bi se smanjio rizik od kontaminacije, potrebno je stalno kontrolirati razinu mikotoskina u hrani. Metode koje se koriste za smanjenje OTA dijele se na fizikalne, kemijske i mikrobiološke metode. Zbog ograničene primjene fizikalnih i kemijskih metoda, koriste se mikrobiološke metode koje su ekološki prihvatljive i učinkovite.

Abstract (english)

Ochratoxin A (OTA) is considered as one of the most dangerous mycotoxins found in food products, and cereal and wine are reported as a main source of OTA in the human diet. Previous studies have shown that it has nephrotoxic, carcinogenic, immunotoxic, mutagenic and neurotoxic effects and it has been classified as a possible human carcinogenic. Besides preventive procedures that are applied to reduce the risk of contamination, what is necessary is a constant control of the levels of mycotoxins in food. The methods used to reduce OTA are physical, chemical or microbiological. Due to the limited application of physical and chemical methods, more environmentally friendly and efficient methods are more used.

• Keywords: Okratoksin A; fizikalne metode; kemijske metode; mikrobiološke metode; detoksifikacija
• Keywords (english): Ochratoxin A (OTA); physical methods; chemical methods; microbiological methods; detoxification
• Language: croatian
• URN:NBN: urn:nbn:hr:159:980918
• Study programme: Title: Biotechnology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-07-21 12:45:15