Povezanost povišene razine urata u krvi s prehrambenim navikama, antropometrijskim i biokemijskim parametrima kod osoba oboljelih od šećerne bolesti

master's thesis

• Title (english): Association of increased blood urate levels with dietary habits, anthropometric and biochemical parameters in persons with diabetes
• Author: Marija Farac
• Mentor: Martina Bituh (mentor)
• Committee member: Ines Panjkota-Krbavčić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Food Chemistry and Biochemistry); Zagreb
• Defense date and country: 2021-02-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Kod nekih osoba oboljelih od šećerne bolesti uočene su povećane razine urata u krvi koje se povezuju s različitim bolestima/stanjima kao što su hipertenzija, hiperlipidemija, pretilost te kronična bolest bubrega i giht. Cilj ovog rada bio je istražiti povezanost između hiperuricemije, prehrambenih navika te antropometrijskih i biokemijskih parametara kod osoba oboljelih od šećerne bolesti tipa 2. Ukupno je bilo uključeno 136 pacijenata oboljelih od šećerne bolesti tipa 2 iz dnevne bolnice Zavoda za endokrinologiju, šećernu bolest i bolesti metabolizma Kliničke bolnice Dubrava u Zagrebu. Prehrambene navike pacijenata utvrđene su putem kvalitativnog upitnika o učestalosti konzumacije hrane i pića te su prikupljeni sociodemografski, antropometrijski i biokemijski parametri. Rezultati ovog istraživanja potvrdili su dosadašnje spoznaje o povezanosti hiperuricemije s antropometrijskim parametrima jer je utvrđeno da osobe s povišenim uratima u odnosu na osobe s normalnim uratima u krvi imaju statistički značajno (p<0,001) viši indeks tjelesne mase (34,7 ± 4,0 kg m-2 vs. 30,7 ± 6,4 kg m-2) i opseg struka (114 ± 10 cm vs. 104 ± 14 cm). S obzirom na promatrane prehrambene navike nije pronađena veza između hiperuricemije i učestalosti konzumacije određenih prehrambenih proizvoda (p>0,001), stoga bi u budućim istraživanjima trebalo koristiti dijetetičke metode koje osim kvalitativnog ispituju i kvantitativni udio namirnica jer je kod pojave hiperuricemije osim vrste bitna i količina namirnica koja se konzumira.

Abstract (english)

Increased blood urate levels have been observed in some people with diabetes, which we associate with various comorbidities such as hypertension, hyperlipidemia, obesity, and chronic kidney disease and gout. The aim of this study was to investigate the association between hyperuricemia, dietary habits, and anthropometric and biochemical parameters in people with diabetes type 2. A total of 136 patients with diabetes type 2 from the day hospital of the Department of Endocrinology, Diabetes and Metabolic Diseases of the Dubrava Clinical Hospital in Zagreb were included. Data on their dietary habits were determined through a qualitative food frequency questionnaire and sociodemographic, anthropometric and biochemical parameters were collected. The results of this study confirmed the current knowledge about the association of hyperuricemia with anthropometric parameters because it was found that people with elevated urate compared to people with normal urate in the blood have a significantly (p <0.001) higher body mass index (34.7 ± 4.0 kg m-2 vs. 30.7 ± 6.4 kg m-2) and waist circumference (114 ± 10 cm vs. 104 ± 14 cm),but there was not a link found between hyperuricaemia and dietary habits (p> 0.001). In future research, different dietary methods should be used, which, in addition to the qualitative, also examine the quantitative part of food, because in the case of hyperuricemia the amount of food consumed is also important.

• Keywords: hiperuricemija; šećerna bolest; mokraćna kiselina; prehrambene navike; pretilost
• Keywords (english): hyperuricemia; diabetes; uric acid; dietary habits; obesity
• Language: croatian
• URN:NBN: urn:nbn:hr:159:362613
• Study programme: Title: Nutrition; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-03-17 11:49:44