IR-spektroskopska analiza seruma bolesnica s karcinomom dojke

undergraduate thesis

• Title (english): IR-spectroscopic analysis of serum of breast cancer patients
• Author: Vita Vučičević
• Mentor: Lidija Barišić (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Chemistry and Biochemistry); (Laboratory for Organic Chemistry); Zagreb
• Defense date and country: 2022-09-07, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

Karcinom dojke najučestalija je vrsta karcinoma među ženama diljem svijeta. Najčešće korištene metode za identifikaciju karcinoma dojke su mamografija, ultrazvučni pregled te biopsija. IR-spektroskopska analiza seruma karcinoma dojke ima brojne prednosti pred navedenim metodama. Zahvaljujući svojoj jednostavnosti, brzini, točnosti, niskoj cijeni, mogućnosti automatizacije te jednostavnoj pripremi uzoraka, IR-spektroskopija smatra se obećavajućom metodom za dijagnosticiranje i praćenje razvoja karcinoma dojke. IRspektroskopija primijenjena je kao nova dijagnostička metoda za razlikovanje kancerogenih uzoraka od zdravih, kao i različitih vrsta karcinoma, uz visoku točnost, specifičnost i osjetljivost. U kombinaciji s Ramanovom spektroskopijom te različitim kemometrijskim pristupima, IR-spektroskopija omogućuje brzo dijagnosticiranje bolesti u ranim fazama razvoja, kao i daljnje praćenje bolesti i primijenjenog tretmana. Otkrićem nove i učinkovite dijagnostičke metode povećava se vjerojatnost izlječenja pacijentica, a povećavaju se i mogućnosti same terapije.

Abstract (english)

Breast cancer is the most common type of cancer among women worldwide. The most commonly used methods for identifying breast cancer are mammography, ultrasound and biopsy. IR-spectroscopic analysis of breast cancer serum has numerous advantages over the methods mentioned above. Owing to its simplicity, rapidness, accuracy, low cost, possibility of automation and simple preparation of samples, IR-spectroscopy is considered a promising method for diagnosing and monitoring the development of breast cancer. IR-spectroscopy has been applied as a new diagnostic method for distinguishing cancerous samples from healthy ones, as well as different types of cancer, with high accuracy, specificity and sensitivity. In combination with Raman spectroscopy and various chemometric approaches, IR-spectroscopy enables rapid diagnosis of the disease in the early stages of development, as well as further monitoring of the disease and the applied treatment. With the discovery of a new and effective diagnostic method, the probability of healing patients increases, as well as the possibilities of the therapy itself.

• Keywords: karcinom dojke; IR-spektroskopija; serum
• Keywords (english): breast cancer; IR-spectroscopy; serum
• Language: croatian
• URN:NBN: urn:nbn:hr:159:022097
• Study programme: Title: Biotechnology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-04-08 08:52:25