Prader-Willi sindrom i njegove kliničke osobitosti povezane s prehranom u djece

undergraduate thesis

• Title (english): Prader-Willi syndrome and its clinical features related to nutrition in children
• Author: Petra Bračić
• Mentor: Ivana Rumbak (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Nutrition Science); Zagreb
• Defense date and country: 2022-09-07, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Prader-Willi sindrom (PWS) rijedak je genetski poremećaj koji nastaje zbog abnormalnosti kromosoma 15, a uz njega vežemo brojna stanja koja utječu na zdravlje i kvalitetu života osoba s PWS. Uslijed poremećenog metabolizma energije i regulacije sitosti, debljina se ističe kao jedan od najvećih problema. Uzrokovana je hiperfagijom još tijekom razdoblja ranog djetinjstva. Osobe s PWS tijekom odrastanja prolaze kroz 7 nutritivnih faza, a svaku od njih karakterizira specifičan odnos prema hrani, prehrambeni unos, ali i mogućnost hranjenja. Istraživanja koja su dosad provedena na ovu temu ukazuju kako je moguće individualiziranom, prilagođenom i balansiranom prehranom, u čemu ključnu ulogu ima nutricionist, regulirati tjelesnu masu te na taj način poboljšati zdravstveno stanje i kvalitetu života pojedinca. Također, ukazuju na potrebu za većim i brojnijim opažajnim istraživanjima, ali također i kliničkim randomiziranim studijama.

Abstract (english)

Prader-Willi syndrome (PWS) is a rare genetic disorder caused by an abnormality of chromosome 15 and it is associated with numerous conditions that affect the health and quality of life of people with PWS. Due to changed energy metabolism and regulation of satiety, obesity stands out as one of the biggest problems. It was caused by hyperphagia during early childhood. People with PWS go through 7 nutritional stages while growing up and each of them is characterized by a specific attitude towards food, food intake and ability to feed. The research conducted so far in this topic indicates that it is possible to regulate body mass with individualized, adapted and balanced diet and thus improve the health condition and quality of life of an individual. Also, they indicate the need for larger and more numerous research, emphasizing the importance of nutritionists as part of the interdisciplinary team.

• Keywords: Prader-Willi sindrom; prehrana; debljina; nutricionist; nutritivne faze
• Keywords (english): Prader-Willi syndrome; diet; obesity; nutritionist; nutritional phases
• Language: croatian
• URN:NBN: urn:nbn:hr:159:169097
• Study programme: Title: Nutrition; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-04-09 08:16:15