In vitro ekotoksikološki profil prirodnih ionskih kapljevina

undergraduate thesis

• Title (english): In vitro ecotoxicological profile of natural ionic liquids
• Author: Manuela Panić
• Mentor: Višnja Gaurina Srček (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Biochemical Engineering); (Laboratory for Cell Technology, Application and Biotransformations); Zagreb
• Defense date and country: 2014-09-11, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

Ionske kapljevine su organske soli niskog tališta sastavljene u cijelosti od iona. Zbog svojih specifičnih svojstava, predstavljaju moguću i dobru zamjenu za organska otapala koja imaju negativan učinak na okoliš i ljude. Obzirom na svojstva, strukturu i vrijeme otkrivanja ionske kapljevine dijele se na ionske kapljevine prve, druge i treće generacije. Prirodne ionske kapljevine pripadaju četvrtoj generaciji i one su ekološki i ekonomski najprihvatljivije. U ovom radu ispitan je utjecaj šest kolinijevih ionskih kapljevina na preživljenje CCO stanične linije riba WST-1 metodom. Na temelju dobivenih rezultata, ispitane ionske kapljevine u usporedbi s ionskim kapljevinama prethodnih generacija pokazale su manju citotoksičnost na CCO stanicama te time i bolji ekotoksikološki profil.

Abstract (english)

Ionic liquids are low-melting organic salts composed entirely of ions. Due to their specific properties, they represent potential and a good replacement for organic solvents that have a negative impact on the environment and people. Considering their properties, structure and time they were discovered, they are divided into ionic liquids of first, second and third generation. Natural ionic liquids belong to the fourth generation and are ecologically and economically most suitable. In this final work the impact of six cholinium ionic liquids on CCO fish cell line was tested by using WST-1 method. Based on the results, tested ionic liquids have shown smaller cytotoxicity on CCO cells than ionic liquids of older generations, thus a better cytotoxicological profile.

• Keywords: prirodne ionske kapljevine; CCO stanice; ekotoksikologija; in vitro metoda
• Keywords (english): natural ionic liquids; CCO cells; ecotoxicology; in vitro method
• Language: croatian
• URN:NBN: urn:nbn:hr:159:512788
• Study programme: Title: Biotechnology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-04-27 12:02:57