Predikcija faznog kuta uz procjenu nutritivnog statusa pacijenata prije vertikalne resekcije želuca

master's thesis

• Title (english): Prediction of phase angle value and nutritional assessment of patients prior to vertical sleeve gastrectomy
• Author: Dora Canjuga
• Mentor: Martina Bituh (mentor)
• Mentor: Irena Martinis (komentor)
• Committee member: Ana Vukelić (predsjednik povjerenstva)
• Committee member: Irena Martinis (član povjerenstva)
• Committee member: Ines Panjkota-Krbavčić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Food Chemistry and Biochemistry); Zagreb
• Defense date and country: 2023-09-25, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Vertikalna resekcija želuca jedna je od najučinkovitijih metoda liječenja pretilosti i pratećih komorbiditeta. Cilj ovoga istraživanja bio je procijeniti nutritivni status pacijenata koji pristupaju zahvatu, uspješnost antropometrijskih i biokemijskih parametara u predviđanju vrijednosti faznog kuta kao važnog markera staničnog integriteta te razinu poboljšanja metaboličkog statusa nakon zahvata. Podaci za istraživanje prikupljeni su retroaktivno iz BIA analize i laboratorijskih nalaza pacijenata koji su pristupili vertikalnoj resekciji želuca u KB Dubrava između 2019. i 2023. godine. Rezultati su pokazali loš nutritivni i metabolički status pacijenata s mnogim promatranim parametrima izvan referentnog raspona, značajno smanjenje tjelesne mase i masnog tkiva nakon zahvata te bolju regulaciju glikemije i smanjenje C-reaktivnog proteina te nemogućnost predviđanja vrijednosti faznog kuta bilo kojim parametrima na koje je utjecaj bio moguć predoperativno. Potvrđena je učinkovitost barijatrijske kirurgije u tretmanu pretilosti i hiperglikemije, no zbog malog broja ispitanika nije bilo moguće predviđati vrijednost faznog kuta i ishod smanjenja tjelesne mase iz predoperativne vrijednosti faznog kuta.

Abstract (english)

Vertical sleeve gastrectomy is one of the most effective obesity and obesity comorbidities treating methods. The aim of this study was to assess patients’ nutritional status prior to surgery, efficacy of anthropometric and biochemical parameters in predicting values of the phase angle as a major cell integrity marker and the extent of metabolic improvements in patients after surgery. Research data was accumulated retroactively from BIA analysis and laboratory values of patients who have undergone vertical sleeve gastrectomy in Clinical Hospital Dubrava between 2019 and 2023. The results have shown a generally poor nutritional and metabolic status with most parameters outside of reference values, a significant reduction in body weight and fat mass along with improved glycemic regulation and a decrease in C-reactive protein, but a lack of evidence to suggest that any of the preoperatively modifiable parameters would be able to predict phase angle values. The study confirmed bariatric surgery to be efficient in treating obesity and hyperglycemia, but due to a low number of participants it was not possible to neither predict phase angle values, nor predict the weight loss amount from preoperative phase angle values.

• Keywords: fazni kut; vertikalna resekcija želuca; pretilost
• Keywords (english): phase angle; vertical sleeve gastrectomy; obesity
• Language: croatian
• URN:NBN: urn:nbn:hr:159:432370
• Study programme: Title: Nutrition; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-05-23 13:11:54