Probiotička i postbiotička svojstva višesojnog probiotičkog pripravka na uzročnike bolesti usne šupljine

undergraduate thesis

• Title (english): Probiotic and postbiotic properties of a multi-strain probiotic preparation on oral disease pathogens
• Author: Ana Šiljeg
• Mentor: Deni Kostelac (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Biochemical Engineering); (Laboratory for General Microbiology and Food Microbiology); Zagreb
• Defense date and country: 2024-06-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

Dentalne infekcije, uzrokovane bakterijama roda Streptococcus i kvascem Candida albicans, dovode do propadanja zuba i bolesti desni. Prevencija se temelji na sprječavanju stvaranja bakterijskih biofilmova. Probiotici mogu smanjiti rizik od karijesa i drugih oralnih bolesti. Ovo istraživanje ispitivalo je antimikrobnu aktivnost bakterija mliječne kiseline protiv dentalnih patogena, njihovu sposobnost formiranja biofilma te koagregaciju sa streptokokima i kvascom Candidom albicans. Rezultati su pokazali da bakterije mliječne kiseline, osim Lacticaseibacillus paracasei, imaju potencijal za formiranje biofilma. Supernatant bakterija mliječne kiseline snažno je inhibirao rast bakterije Staphylococcus aureus. Koagregacija streptokoka s bakterijom Lacticaseibacillus rhamnosus bila je posebno izražena, sugerirajući da probiotički pripravci mogu imati važnu ulogu u očuvanju oralnog zdravlja

Abstract (english)

Dental infections, caused by bacteria of the genus Streptococcus and the yeast Candida albicans, lead to tooth decay and gum diseases. Prevention focuses on inhibiting the formation of bacterial biofilms. Probiotics can reduce the risk of cavities and other oral diseases. This study examined the antimicrobial activity of lactic acid bacteria against dental pathogens, their ability to form biofilms, and their coaggregation with streptococci and Candida albicans. The results showed that lactic acid bacteria, except Lacticaseibacillus paracasei, have the potential to form biofilms. The supernatant of lactic acid bacteria strongly inhibited the growth of Staphylococcus aureus. Coaggregation of streptococci with Lacticaseibacillus rhamnosus was particularly pronounced, suggesting that probiotic preparations could play an important role in maintaining oral health.

• Keywords: biofilmovi; antimikrobno; koagregacija; autoagregacija; dentalni patogeni
• Keywords (english): biofilms; antimicrobial; coaggregation; autoaggregation; dental pathogens
• Language: croatian
• URN:NBN: urn:nbn:hr:159:317763
• Study programme: Title: Biotechnology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-11-11 14:24:17