Međusobna povezanost oksidacijskog stresa i vitamina C s antioksidacijskim učinkom

undergraduate thesis

• Title (english): Interconnection of oxidative stress and vitamin C antioxidant effect
• Author: Marta Vuković
• Mentor: Irena Landeka Jurčević (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Food Chemistry and Biochemistry); Zagreb
• Defense date and country: 2011-07-13, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Vitamin C je esencijalan sastojak hrane uključen u mnoge biološke i biokemijske procese kao antioksidans. S obzirom da je oksidacijsko oštećenje povezano s nastankom različitih bolesti, vitamin C ima potencijalno preventivan, ali i terapijski učinak. Voće i povrće su preporučeni izvori vitamina C koji imaju preventivnu ulogu u razvoju malignih tumora i bolesti krvožilnog sustava, premda ne isključivo zbog vitamina C. Povrh toga, sintetski vitamin C uzet u količinama većim od preporučenog dnevnog unosa (RDA) djeluje povoljno na zarastanje rana, ublažavanje simptoma prehlade, ali i u prevenciji prehlade u osoba izloženih prekomjernom fizičkom stresu. Također, vitamin C je učinkovit u smanjivanju koncentracije fibrinogena povezanog s povećanim rizikom od nastanka bolesti krvožilnog sustava. Pozitivni učinci mogu se također ostvariti intravenskim unosom vitamina C kod bolesnika s dijabetesom i nekim oblicima malignih tumora. Međutim, pozitivni učinci vrlo često ovise o mnogim čimbenicima, kao što su doza, dob, zdravstvene navike i dr.

Abstract (english)

Vitamin C is anessential nutrient involved in many biological and biochemical processes as an antioxidant. As oxidative damage is implicated in the development of various diseases, vitamin C could have a preventive or even therapeutic effect. Fruits and vegetables are the recommended sources of vitamin C. Fruits and vegetables are protective against cancer and cardiovascular disease, however not because of vitamin C alone. On the other hand, oral vitamin C supplements in amounts higher than Recommended Daily Allowance (RDA) are beneficial in wound healing, reducing the duration of common cold symptoms, but all so in prevention of common cold in heavily physically stressed persons. Furthermore, vitamin C is effective in decreasing se rum fibrinogen, which is related to in creased cardiovascular risk. Positive effects may be also achieved by intraarterial or intravenous administration of vitamin C in patients with diabetes mellitus and cancer. However, positive effects frequently depend on many factors, such are dose, age, health habits, etc.

• Keywords: vitamin C; antioksidans; oksidacijski stres; kardiovaskularne bolesti; tumori
• Keywords (english): vitamin C; antioxidant; oxidative stress; cardiovascular disease; cancer
• Language: croatian
• URN:NBN: urn:nbn:hr:159:624750
• Study programme: Title: Nutrition; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-05-19 10:07:26