Izrada računalnog programa za prikupljanje, obradu, pohranu i grafički prikaz bioloških podataka

master's thesis

• Title (english): Development of computer program for the acquisition, processing, storage and raphical presentation of biological data
• Author: Janko Diminić
• Mentor: Daslav Hranueli (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Biochemical Engineering); (Section for Bioinformatics); Zagreb
• Defense date and country: 2007-12-05, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Biotechnology

Abstract

U tijeku je razvoj integralnog računalnog programskog paketa, CompGen, za modeliranje procesa homologne rekombinacije između poliketidnih/peptidnih genskih nakupina u uvjetima in silico. Okosnica će programskog paketa CompGen biti specifično strukturirana baza podataka koja povezuje biosintetski put sinteze sa sekvencijama DNA genskih nakupina. U ovom je radu strukturirana specifična baza podataka poliketidnih/ peptidnih genskih nakupina po uzoru na BioSQL. Razvijeni su i računalni programi za: prikupljanje i strukturiranje bioloških podataka; detaljan opis ("anotaciju") modula, domena i njihovih poveznica; anotaciju biosintetskih putova i grafičko prikazivanje dvodimenzionalnih i trodimenzionalnih kemijskih struktura linearnih lanaca poliketida/peptida objektno orijentiranim računalnim jezikom Java i skriptnim računalnim jezikom JavaScript.

Abstract (english)

An integral generic program package, CompGen, is under development to model the process of homologous recombination between polyketide/peptide gene-clusters in silico. The heart of CompGen will be a specially structured database that will connect the biosynthetic order to the DNA sequences. In this work the specific database was structured based on BioSQL. The computer programs for the acquisition and structuring of biological data; the annotation of modules, domains and their dockers and linkers; the annotation of biosynthetic order and for the graphical presentation of two-dimensional and three-dimensional chemical structures of linear polyketide/peptide chains were developed using computer languages Java and JavaScript.

• Keywords: baza podataka; modularne genske nakupine PKS i NRPS; računalni programski paket; računalni program; poliketidi i neribosomalno sintetizirani peptidi
• Keywords (english): polyketides and non-ribosomal synthesized peptides; modular PKS and NRPS gene-clusters; database; computer program package; computer program
• Language: croatian
• URN:NBN: urn:nbn:hr:159:302916
• Study programme: Title: Food Technology; specializations in: Food Engineering; Course: Food Engineering; Study programme type: university; Study level: graduate; Academic / professional title: diplomirani inženjer prehrambene tehnologije; smjer prehrambeno inženjerstvo (diplomirani inženjer prehrambene tehnologije; smjer prehrambeno inženjerstvo)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-09-06 07:18:50