Aronija: bioraspoloživost i antioksidativno djelovanje polifenola

undergraduate thesis

• Title (english): Aronia: bioavailability and antioxidant activity of polyphenols
• Author: Tena Gikić
• Mentor: Veronika Kovač (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Chemistry and Biochemistry); (Laboratory for Organic Chemistry); Zagreb
• Defense date and country: 2013-07-10, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Nutrition

Abstract

Aronija je prepoznatljiva bobica sa visokim sadržajem polifenolnih spojeva, a posjeduje jednu od najjačih antioksidativnih aktivnosti među voćem. Čini se da je bioraspoloživost polifenola aronije niska, ali postoji dovoljno dokaza o njezinom zdravstvenom utjecaju kao što su kardioprotektivni, antimutageni, hepatoprotektivni i antikancerogeni učinci. Ovaj rad daje informacije o bioraspoloživosti i antioksidativnom djelovanju polifenola aronije, te objašnjava moguće mehanizme djelovanja in vivo u prevenciji i liječenju bolesti koje su povezane sa oksidacijskim stresom. Također pokazuje dostupne podatke o antioksidacijskoj aktivnosti aronije in vitro, u izoliranim stanicama i staničnim linijama, te in vivo, u ljudskim subjektima i u životinjama.

Abstract (english)

Black chokeberry (Aronia melanocarpa) is a distinctive berry with a high content of polyphenol compounds and possesses one of the highest in vitro antioxidant activities among fruits. The bioavailability of aronia polyphenols seems to be low, but there is ample evidence for chokeberry health benefits including antidiabetic, cardioprotective, hepatoprotective, antimutagenic, and anticarcinogenic effects. This work presents the available information for the bioavailability and antioxidant activity of chokeberry polyphenols and explains the possible mechanisms of action in vivo in the prevention and treatment of oxidative stress-related diseases. The work shows the available data for chokeberry antioxidant activity in vitro, in isolated cells and cell lines, and in vivo, in both human subjects and animals.

• Keywords: aronija; polifenoli; bioraspoloživost; antioksidativna aktivnost
• Keywords (english): black chokeberry; polyphenols; bioavailybility; antioxidant activity
• Language: croatian
• URN:NBN: urn:nbn:hr:159:432055
• Study programme: Title: Nutrition; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-05-03 08:01:41