prikaz prve stranice dokumenta New types of heteroannularly substituted ferrocene peptides
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master's thesis
New types of heteroannularly substituted ferrocene peptides
2012. urn:nbn:hr:159:891326
Bilić, Josipa
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Chemistry and Biochemistry
Laboratory for Organic Chemistry

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Bilić, J. (2012). New types of heteroannularly substituted ferrocene peptides (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:891326

Bilić, Josipa. "New types of heteroannularly substituted ferrocene peptides." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2012. https://urn.nsk.hr/urn:nbn:hr:159:891326

Bilić, Josipa. "New types of heteroannularly substituted ferrocene peptides." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2012. https://urn.nsk.hr/urn:nbn:hr:159:891326

Bilić, J. (2012). 'New types of heteroannularly substituted ferrocene peptides', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 13 October 2024, https://urn.nsk.hr/urn:nbn:hr:159:891326

Bilić J. New types of heteroannularly substituted ferrocene peptides [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2012 [cited 2024 October 13] Available at: https://urn.nsk.hr/urn:nbn:hr:159:891326

J. Bilić, "New types of heteroannularly substituted ferrocene peptides", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2012. Available at: https://urn.nsk.hr/urn:nbn:hr:159:891326

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Metadata
TitleNew types of heteroannularly substituted ferrocene peptides
AuthorJosipa Bilić
MentorSenka Djaković (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Chemistry and Biochemistry)
(Laboratory for Organic Chemistry)
Zagreb
Defense date and country2012-07-02, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Among artificial peptide building blocks the 1,1'-disubstituted ferrocene scaffold has attracted particular interest because of its unique properties and potential usage in biomedical, nano- and material sciences. Herein we report the synthesis and characterization of unsymmetrical disubstituted ferrocene peptides type I (NOH(CH3)C-Fn-CO-AA-OCH3) and II (NOH(CH3)C-Fn-NH-AA-Boc) with oxime subunit on 1’-cyclopentadienyl ring as potential hydrogen donor/acceptor of hydrogen bond. Prepared bioconjugates I and II were characterized by FTIR, NMR and CD spectroscopy. Conformational analysis of prepared unsymmetrically substituted ferrocene compounds type I and II has shown presence of week to medium intramolecular hydrogen bonds. Positive Cotton effects have been associated with P-helical ferrocene units while negative Cotton effects are considered to be indicative of M-helical ferrocene chromophores which suggest that in this case compounds I form predominantly P-helical conformations while compounds II form M-helical conformations.
Keywords
Languageenglish
URN:NBNurn:nbn:hr:159:891326
Study programmeTitle: Molecular Biotechnology
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka molekularne biotehnologije (magistar/magistra inženjer/inženjerka molekularne biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2017-05-09 09:22:48