Salicilna kiselina-primjena u medicini, kozmetici i utjecaj na zdravlje

undergraduate thesis

• Title (english): Salicylic acid-application in medicine, cosmetics and impact on health
• Author: Mateja Marić
• Mentor: Irena Landeka Jurčević (mentor)
• Granter: University of Zagreb; Faculty of Food Technology and Biotechnology; (Department of Food Quality Control); (Laboratory for Food Chemistry and Biochemistry); Zagreb
• Defense date and country: 2022-07-08, Croatia
• Scientific / art field, discipline and subdiscipline: BIOTECHNICAL SCIENCES; Food Technology

Abstract

Salicilna kiselina je o-hidroksibenzojeva kiselina ili 2-hidroksibenzojeva kiselina koja se može pronaći u velikom broju biljaka kao biljni hormon. Salicilna kiselina može se sintetizirati iz vrbe, fenilalanina, Kolbe-Schmitt reakcijom i hidrolizom aspirina. Acetilirani derivat salicilne kiseline odnosno aspirin je jedan od najkorištenijih lijekova koji se koristi za liječenje boli, upala, groznice te smanjuje rizik od srčanog udara. Neke analize pokazuju učinkovitost salicilne kiseline u lječenju akni. Moguća je oralna i lokalna primjena salicilne kiseline. Oralnom primjenom salicilne kiseline i njenih derivata najčešće dolazi do gastrointestinalne iritacije dok lokalna primjena na velikoj površini kože može uzrokovati apsorpciju u krvotok što izaziva toksičnost odnosno salicilizam.

Abstract (english)

Salicylic acid is o-hydroxybenzoic acid or 2-hydroxybenzoic acid which can be found in a large number of plants as a plant hormone. Salicylic acid can be synthesized from willow, phenylalanine, with Kolbe-Schmitt reaction and hydrolysis of aspirin. Acetylated derivate of salicylic acid or aspirin is one of the most widely used drugs used to treat pain, inflammation, fever and reduce the risk of heart attack. Some analyses show the effectiveness of salicylic acid in treating acne. Salicylic acid can have oral and topical applications. With oral application most common is gastrointestinal irritation., while topical application on a large area of skin may cause absorption into the bloodstream, causing toxicity or salicylism.

• Keywords: salicilna kiselina; sinzeta; aspirin; akne; toksičnost
• Keywords (english): salicylic acid; synthesis; aspirin; acne; toxicity
• Language: croatian
• URN:NBN: urn:nbn:hr:159:808913
• Study programme: Title: Food Technology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-09-27 08:23:06